Meet the Busby Family, which includes mom Danielle, dad Adam, 4-year old daughter Blayke, and 5 baby girls. 40 bottles a day, 420 diapers a week and feedings every 3 hours became the new normal for Danielle & Adam when they welcomed home the only all-female set of quintuplets.

Matt & Amy Roloff enlist the help of their four children Jeremy, Zack, Molly & Jacob to help expand the business of Roloff farms. As the kids grow older, the family grows larger and the Roloffs learn how to keep their family relationships strong.

Karen and Deon Derrico are parents to four sets of multiples -- 14 kids, including a set of quintuplets -- conceived NATURALLY! The birth of their triplets brings the couple new challenges that will test everything they know about parenthood.

The Johnstons are an average American family of seven except everyone is a little person. Distinguished from others as they only depend on each other to prove size doesn't matter. They juggle family and health issues in the middle of a home renovation.

Courtney and Eric Waldrop were High School sweethearts from Albertville, Alabama who already have a young son and two twin boys. But now that mom is pregnant with sextuplets their entire life is about to be turned upside down.

The nine flaxen-haired children in the Plath family have never had a soda, don't know who Spiderman or Tom Brady is and have never watched TV, living remotely in rural Georgia with their "follow their own rules" parents Kim and Barry Plath.

In this digital series, delve into the lives of the 90 Day Fiancé couples that we never got to see past their “I do’s."

Catch up with your favorite mothers and daughters from the TLC hit show, sMothered, and meet the new duos that take the phrase "like mother, like daughter" to the extreme!

See more hair and nail transformations from the Martones!

Dr. Sandra Lee shares all the gory details behind some of her most difficult pops. Watch intimate excavation videos of blackheads so big and cysts so goopy, they have to be seen to be believed.

The Slaton's are larger-than-life sisters who have always relied on each other and food for support. Amy, age 31, is desperate to have children, but hasn't been able to due to her weight. While Tammy, age 32, is one step away from being bedridden.

We get a look at the final weeks of pregnancy for three teen couples and the first few months of parenthood with teens who happened to have been raised by teens.

Follow participants as we document the life-saving, but traumatic experience of surgery, the ups and downs of struggling with addiction and dependence, and the inevitable impact that change has on personal relationships.

Dancing her way through the haters, Whitney Thore is embracing her body in a world that judges people by their size. After being diagnosed with PCOS and the success of her “fat girl” dancing videos, Whitney’s choosing to live vivaciously and holding nothing back.

The Johnstons are an average American family of seven except everyone is a little person. Distinguished from others as they only depend on each other to prove size doesn't matter. They juggle family and health issues in the middle of a home renovation.

Dr. Sandra Lee isn’t just one of America’s top dermatologists; she’s an Instagram and YouTube celebrity who has pioneered the fastest growing medical fascination in decades.

The nine flaxen-haired children in the Plath family have never had a soda, don't know who Spiderman or Tom Brady is and have never watched TV, living remotely in rural Georgia with their "follow their own rules" parents Kim and Barry Plath.

The Martones are a loud, fun-loving Italian family from Long Island. Sisters Lexi, a talented nail artist, and Bria, a hair colorist/makeup artist, run Salon Martone while juggling family dynamics, over the top clients, and their own relationships.

Hunky men who love fat women don't have a fetish they have a preference! Three couples endure difficult challenges both inside and outside of their relationships, as they're forced to answer the ultimate question: can love conquer all?

Patients of Dr. Brad Schaeffer and Dr. Ebonie Vincent undergo surgery to have their feet radically transformed and their lives changed forever.

Follow the next generation of Duggars as they celebrate some of life’s milestone moments, including the realities of growing up and raising their own families.

Meet the Busby Family, which includes mom Danielle, dad Adam, 4-year old daughter Blayke, and 5 baby girls. 40 bottles a day, 420 diapers a week and feedings every 3 hours became the new normal for Danielle & Adam when they welcomed home the only all-female set of quintuplets.