Janine makes her way to the airport in an effort to go see Dr. Nowzaradan in Houston.

My 600-lb Life premieres Weds on TLC.

Alicia recognizes that her weight was a topic of concern, even from a young age.

Kirsten struggles to leave the house, realizing she is now too large to fit in the front seat of a car.

Now that Chuck has lost nearly 400 pounds, he's able to do his job better and is ready to be the kind of man who supports a wife and children. He delivers an emotional testimony at church about his lifestyle change.

Alicia discusses her relationship with her boyfriend Tim as well as her love affair with food.

When Tara weighed 606 pounds, dating wasn't even a thought that entered her mind. Now that she's lost 300 pounds, she's looking for a good man to start a new life with.

At over 700lbs, Teretha's life is confined to a bed which is a far cry from her former job representing Detroit's healthy eating program.

Alicia and her mother have an emotional conversation about Alicia's childhood and her weight gain.

Christina's weight loss has gone too far, too fast, and now threatens her life.

Liz discusses the events in her childhood that have caused her to gain the extra weight.

With the help of her physical therapist, Liz attempts to stand.

After losing 300lbs, Paula must endure more surgery to deal with a body entirely covered in loose and sagging excess skin.

Doug is not the only one dealing with a weigh loss issues, as Ashley describes her own struggle and how Doug has been bringing them both down.

Zsalynn is excited for a fresh start but her 360-body lift at a Beverly Hills clinic proves more challenging than expected.

Liz speaks with a professional counselor to discuss some of the reasons she turns to food.