Jazz & Jeanette return home to the devastation left by Irma. In an effort to help, Jazz and her parents drive to The Keys to help in the clean up. Later, the family travels to San Francisco to meet with Dr. Bowers who has some shocking news for Jazz.

Learning she needs to lose 30 lbs to be eligible for bottom surgery, Jazz commits to losing weight. Jazz & Jeanette participate in a debate over controversial research that suggests children shouldn't be placed on hormone blockers before puberty.

Jazz and her family head to NYC for a vacation and surgical consultation. While the family enjoys the sights and rafting, Jazz fears she may need to undergo a painful procedure. Later, Jazz & Greg argue over whether Jazz is ready for bottom surgery.

Jazz explores dating girls & agrees to hang out with a potential female love interest. Jazz & Jeanette meet with Jazz's therapist for the therapy letter needed for Jazz's bottom surgery, but find the letter may not be as easy to obtain as they hoped.

The entire family supports Jazz's weight loss effort by having a family soccer match. Meanwhile, Jazz resumes hypnotherapy to control her binge eating. She also helps her friend raise money for hormones, and gathers the courage to ask out Victoria.

Jazz undergoes past life regression hypnosis for her weight issues and finds insight in a troubled past. She also pressures her parents to allow her to go to virtual school, and goes on her first date with a girl hoping for a romance.

Greg and Jazz attempt to surprise Jeanette with a wedding vow renewal ceremony; Jazz gets an unexpected gift on her 17th birthday; Dr. Volker makes a decision about Jazz's therapy letter; Dr. Bowers has one final ultimatum regarding Jazz's surgery.

Jazz's doctors perform her groundbreaking bottom surgery while her family anxiously awaits news. With the OK from her doctors Jazz is released to recover in a hotel. Just 4 days later Jazz suffers complications & is rushed back to the operating room.

Jazz is rushed into emergency surgery due to a major complication. While staying with Jazz for her recovery in New York, Jeannette learns Jack is fighting for his life in a health crisis of his own.

Adam and Danielle Busby defy all odds by giving birth to the first set of all girl quintuplets in the US. After four months in the NICU, the quints come home and along with four-year-old sister Blayke, turn Adam and Danielle's lives upside down.

Adam and Danielle struggle to keep up with the demands of the quintuplets while also making time for 4-year-old daughter, Blayke. Later, a baby photo shoot with the quints turns into pure chaos when Grandma Mimi shows up late to help.

Adam returns to work, leaving Danielle to care for the quintuplets and Blayke by herself for the first time. On Adam's first day back, Hazel falls ill with a fever, leaving the family scrambling and Danielle feeling overwhelmed and alone.

Adam & Danielle realize they need a larger home, but house hunting proves stressful when they realize what a larger house will cost. Later, the family heads back to their hometown & Danielle comes up with an idea that could solve all their problems.

Can anybody potty train the quints?

Uncle Nick and Aunt Ashley get a crash course in watching the Busby quints!