Jazz undergoes past life regression hypnosis for her weight issues and finds insight in a troubled past. She also pressures her parents to allow her to go to virtual school, and goes on her first date with a girl hoping for a romance.

Greg and Jazz attempt to surprise Jeanette with a wedding vow renewal ceremony; Jazz gets an unexpected gift on her 17th birthday; Dr. Volker makes a decision about Jazz's therapy letter; Dr. Bowers has one final ultimatum regarding Jazz's surgery.

Jazz prepares for a final weigh-in for her gender confirmation surgery. Meanwhile, Dr. Bowers shocks Greg and Jeanette with changes to the surgical plan. Jazz and her friends head out for a night of fun at prom, but it turns into a nightmare.

With Jazz's surgery 3 weeks away, Jeanette feels scared and unprepared. Sander's hurt that Griffen's spending more time with his girlfriend. Jazz, desperate for love, runs into her old flame. Later, Jazz gets a scary prediction about her surgery.

Adam and Danielle Busby defy all odds by giving birth to the first set of all girl quintuplets in the US. After four months in the NICU, the quints come home and along with four-year-old sister Blayke, turn Adam and Danielle's lives upside down.

Adam and Danielle struggle to keep up with the demands of the quintuplets while also making time for 4-year-old daughter, Blayke. Later, a baby photo shoot with the quints turns into pure chaos when Grandma Mimi shows up late to help.

Adam returns to work, leaving Danielle to care for the quintuplets and Blayke by herself for the first time. On Adam's first day back, Hazel falls ill with a fever, leaving the family scrambling and Danielle feeling overwhelmed and alone.

Adam & Danielle realize they need a larger home, but house hunting proves stressful when they realize what a larger house will cost. Later, the family heads back to their hometown & Danielle comes up with an idea that could solve all their problems.

Can anybody potty train the quints?

Uncle Nick and Aunt Ashley get a crash course in watching the Busby quints!

Keeping the quints entertained is a full-time job!

Five two-year-olds make the Busby household messy, loud, and oh so cute!

See the world through the eyes of these mini explorers!

Amish & Ex-Amish friends and family get together at Mary Schmucker's where her husband Chester is in for a rude awakening. Andrew has a score to settle with Jeremiah, Rebecca & Sabrina are expecting big things and Kate awaits a great opportunity.

Mary takes a trip to New York City. Katie Ann tags along with Mary and Kate, and talks to a New York guy! In Pennsylvania, Abe, Rebecca, Sabrina, and Jeremiah talk babies and shunning … while Andrew and Chapel have an important appointment.

Abe and Rebecca introduce their newborn baby to the Schmucker family, but when Sabrina shows up, her pregnancy takes a scary turn. Jeremiah takes on the Schmucker ladies. And Mary argues with Chester about the church, while Chapel gets some news.