Next on Dr. Pimple Popper: This Is Zit, Dr. Sandra Lee gets to work on one of the biggest blackheads she's ever seen!

In this episode of Dr. Pimple Popper: This Is ZIt, Dr. Sandra Lee reveals a never-before-seen-pop and explains what really makes up a lipoma and why some of these pesky pops are so difficult to extract!

Remember popaholics, if you don't get the sac, the cyst will come back! In this episode of Dr. Pimple Popper: This Is Zit, Dr. Lee demonstrates how to take on an unrelenting epidermoid cyst in this never-before-seen pop!

In this episode of Dr. Pimple Popper: This Is Zit, Dr. Lee takes on four epidermoid cysts in one appointment and each one is bigger than the last!

When a massive lipoma puts up a fight, Dr. Lee grabs her gloves and gets to work! In this episode of Dr. Pimple Popper: This Is Zit, this determined dermatologist explains why these stubborn pops are often the most satisfying.

In order to treat a keloid, Dr. Lee has to freeze it from the inside out using liquid nitrogen. Plus, watch Dr. Lee pop a bonus baby evil eye.

Dr. Lee shows the difference between cheek cysts and scalp pilar cysts in these back-to-back pops.

When Dr. Lee gets her hands on this woman's milia, they pop out like little pearls!

This painter's time outdoors has led to a face full of blackheads for Dr. Lee to pop.

One man drives from two hours away for Dr. Lee to pop his never-before-touched cheek cyst.

Dr. Lee needs a splash guard for a potentially infected cyst.

Dr. Lee's first big steatocystoma multiplex patient returns to the office for some buttery pops.

Dr. Lee pops a hidden ear cyst and explains why this part of our bodies are so prone to cysts and blackheads.

Even this popaholic was nervous about the placement of this pore of winer.

This cyst-prone patient is terrified of getting another post-pop scar. Can Dr. Lee make sure that doesn't happen?

Dr. Lee extracts tons of blackheads from one woman and explains what can cause "ombre blackheads."