Nick works with several engineers in trying to drive a car without any limbs. He's not confident it will work.

Recently divorced Christine decides to make some changes in her life. She get into shape and meets a new guy. By the end of the summer she can't understand why her clothes don't fit her like they used to.

Jamie is all alone when she goes into labor. Without any help she delivers her baby.

Ivonne and her husband want a second child but Ivonne's medical condition might take that dream away. Who could have guessed that when she goes in for a check up the doctor would have surprising good news.

A woman becomes a first time mom in a cab on the way home from a club only to be surprised again years later at a friend's BBQ.

Barbara is so certain she does not want more children that she has her tubes tied. Then she gets the shock of her life, a miracle pregnancy.

Owen & Giovanni are Boys of Steel.

Imagine living with one of the rarest medical conditions in the world; having no one to confide in who understands the pain, struggles, and isolation of everyday life. In each episode of the new TLC series Two In A Million, two people who share the same medical struggles meet and spend one week together, sharing hardships and incredible triumphs, visiting world-renowned doctors, and finding answers to important questions

Haatchi, Owen's 3 legged dog, has helped Owen gained self esteem and confidence, and has stopped him from being bullied.

Bullies have told Owen he'll never win a race, him and his pal Giovanni take it to the track in a friendly competition!

2 women who live with a rare diease, Jarcho Levin Syndrome, will meet for the first time and form a lifelong friendship overcoming their struggles.

Tiffany, 30, and Yajaira, 27, have Jarcho Levin Syndrome. Can meeting bring friendship and answers to lifelong questions?

Tiffany, 30, and Yajaira, 27, have Jarcho Levin Syndrome. Can meeting bring friendship and answers to lifelong questions?

Imagine if your ribs and spine were malformed and your organs squashed in a tiny torso?

Austin and Elena have both been through bullying and it's impacted their lives, but they have come together to share a powerful message of courage and overcoming through love and support.

These two become fast friends in this Two In A Million First Look!