A visit to urgent care gives Amy life-changing news.

Amy is worried about dropping the news that she is pregnant.

Tammy gets devastating news from Dr. Procter.

Tammy must step on the scale again after not sticking to her diet.

Amy and Michael drop a bomb that changes everything.

Tammy's boyfriend, Jerry, comes to visit just in time for Halloween.

Amy has an eccentric photo shoot, and Tammy reveals a big secret to Jerry.

When Tammy and Amy go see a psychic, they both get disturbing news.

Amy gets unsettling news about the birth of her baby.

While recovering from COVID-19, Tammy's weight spirals.

Sisters Amy and Tammy must lose weight to qualify for bariatric surgery.

With her weight spiraling, Tammy makes a life-altering decision.

Amy and Tammy Slaton are back to share their lives and weight struggles. 1000-lb Sisters returns November 15 at 10/9C.

At 650 lbs, Melissa is ready to begin her seven-year weight loss journey.

Two years after her surgery, Melissa struggles to get to her ideal weight.

Motivated by love, 675-lb Donald begins his weight loss journey.