Zsalynn and Christina continue to make progress with their weight loss.

Olivia works toward her goal weight, and James hopes to have skin surgery.

Penny struggles while Tara continues to lose weight and enjoys dating.

Brianne gains independence. Annjeanette chooses love over health.

The lives of obese cousins Naomi, Drew and Chitoka are in danger.

Drew wants to have the weight loss surgery, and Chitoka asks for help.

Chitoka tries to become more mobile, starting by leaving her bedroom.

Two people undergo surgery to remove excess skin left after weight loss.

Two women undergo surgery to remove excess skin from extreme weight loss.

Two people have surgery to remove skin remaining after major weight loss.

At 650 lbs, Melissa is ready to begin her seven-year weight loss journey.

Two years after her surgery, Melissa struggles to get to her ideal weight.

Motivated by love, 675-lb Donald begins his weight loss journey.

At 715 lbs, Henry hopes to transform himself and attend his school reunion.

Ashley aims to turn her life around after being let go due to her weight.

At nearly 1,000 pounds, Samantha is dangerously close to dying.