Born: November 25, 1971
Place of Birth: Los Angeles, California
1981 - Played Kim Perry in the horror movie Jaws of Satan
1983 - Played a young Grace Kelly in the TV movie Grace Kelly
1987 - Made an appearance on "Family Ties" and began a life-changing role on "Married with Children," which ran from 1987-1997
1988 - Appeared on an episode of "21 Jump Street"
1991 - Played the eldest child, Sue Ellen Crandell, in the movie Don't Tell Mom The Babysitter's Dead
1998 - Acted in the movies Claudine's Return, The Big Hit, and Jane Austen's Mafia! and starred in the TV series "Jesse" as Jesse Warner
1999 - Played Lilah in Out in Fifty
2000 - Played Emily in The Giving Tree
2002 - Starred in The Sweetest Thing with Cameron Diaz and Selma Blair. Played Rachel Green's sister on the TV show "Friends"
2004 - Starred in the movie Employee of the Month and became well-known in the large-scale comedy community starring with Will Ferrell in Anchorman: The Legend of Ron Burgundy
2007 - Returned to television in the sitcom "Samantha Who?" which aired on ABC from 2007-2009. Applegate played Samantha, a woman who suffers from amnesia
2011 - Applegate played the starring role in NBC's comedy series "Up All Night"
2013 - The much awaited Anchorman: The Legend Continues, a continuation of the 2004 Anchorman movie is set to be released in December